Twitter was a trending topic Tuesday — and not just on Twitter. Actual people were physically gathered at the Skirball Cultural Center for the two-day conference dedicated to the microblogging site. Company cofounder Biz Stone opened the conference with a 40-minute speech about the origins of Twitter and its goal to make a positive global impact, citing the site’s importance in organizing political protests worldwide. The Twitter Conference boasted big names Tuesday, including San Francisco Mayor Gavin Newsom and pro skateboarder Tony Hawk.