While there have been significant breakthroughs in nano-manufacturing, there has been much less progress on measurement technologies that can provide information about nanostructures made from multiple integrated materials. Researchers now report new diagnostic tools that can support cutting-edge nano-manufacturing. Using atomic force microscope based infrared spectroscopy to characterize polymer nanostructures and systems of integrated polymer nanostructures, researchers were able to chemically analyze polymer lines as small as 100 nm.