Scientists demonstrated that the microRNAs expression can be potentially responsible for the abnormal acini formation of breast cancer cells. They observed that the overexpression of the miR-205 influences the morphology of acini, linking this miRNA to breast epithelial cell transformation. miR-205 appears not to be a simple tumor-suppressor miRNA in breast as previously believed, but it can be overexpressed in transformed cells and can influence the morphology of acini.