Osteonecrosis, or bone cell death, can result in debilitating damage to prosthetic joint and tooth implants, among others. Failures with these implants often require painful follow-on surgeries and increased medical costs. Nanodiamonds have been developed for the sustained and simultaneous delivery of two proteins that promote bone growth. While conventional approaches require the surgical implantation of a sponge to deliver these proteins, administering the nanodiamonds via injection or as a rinse is non-invasive.