High levels of glutamate in brain may kick-start schizophrenia: Implications for early diagnosis and new treatment strategies

An excess of the brain neurotransmitter glutamate may cause a transition to psychosis in people who are at risk for schizophrenia. The findings suggest a potential diagnostic tool for identifying those at risk for schizophrenia and a possible glutamate-limiting treatment strategy to prevent or slow progression of schizophrenia and related psychotic disorders.