Our chromosomes contain all of our genetic information, and it’s up to telomeres – structures of proteins that cap off and protect our DNA at the tips of chromosomes – to preserve the vital instructions necessary for life. There are even specific molecules like TERRA (Telomeric repeat-containing RNA) that exist specifically to regulate telomeres and promote chromosome end protection. Now, a new study has found that TERRA can be found outside of cells and serve as a potentially important cell signaling molecule that induces an inflammatory response, and this activity may play an important role in the development of cancer.