A new study has helped determine that UBE3A gene loss specifically from GABAergic neurons is what’s critical for seizures in Angelman patients. But UBE3A loss from other neuron types may drive other phenotypes associated with the condition.
A new study has helped determine that UBE3A gene loss specifically from GABAergic neurons is what’s critical for seizures in Angelman patients. But UBE3A loss from other neuron types may drive other phenotypes associated with the condition.